Disease Guide

Grape & Raisin Toxicity in Dogs and Cats: Vomiting, Appetite Loss & Kidney Function [2025]

Grapes and raisins are nephrotoxic to dogs and can cause acute kidney failure even in small amounts. Seek veterinary care immediately after ingestion — early treatment leads to a better prognosis.

Last updated: 2026/01/05
Pethealthmap Editorial Team
Sources: ASPCA, AVMA, National Taiwan University Veterinary Hospital

When to See a Vet

Seek Emergency Care Immediately

  • Persistent, severe vomiting with inability to drink water or eat normally
  • Noticeably reduced urine output or near-complete absence of urination within a short period
  • Seizures, coma, or sudden loss of consciousness

Schedule a Clinic Visit Soon (within 24–72 hours)

  • Significantly reduced appetite or complete refusal to eat for several hours
  • Recurring intermittent vomiting more than twice without improvement
  • Marked lethargy or noticeable change in mental status

01What symptoms indicate something is wrong?

After ingesting grapes or raisins, pets commonly first show gastrointestinal and behavioural changes, which may progress to kidney dysfunction.

  • Lethargy, obvious drowsiness, or reduced energy
  • Decreased appetite or complete refusal to eat
  • Frequent or repeated vomiting
  • Diarrhoea or obvious abdominal discomfort and bloating
  • Signs of dehydration such as dry mouth and reduced skin elasticity
  • Obvious discomfort or pain response during movement

Seek emergency care immediately if you notice the following symptoms:

  • ⚠️ Persistent vomiting with inability to drink water or eat
  • ⚠️ Markedly reduced urine output or near-complete absence of urination within a short period
  • ⚠️ Seizures, loss of consciousness, or sudden collapse

02How should you assess the situation at home? Key observations and emergency warning signs

Observing and recording key information at home helps the vet quickly assess the severity of the poisoning and prioritise treatment.

  • Record the time of suspected ingestion and estimate the amount consumed
  • Note the timing of any changes in alertness or willingness to eat
  • Log the number of vomiting episodes, timing, and contents of vomit
  • Monitor and record any blood in stools or abnormal faeces
  • Estimate changes in water intake and urine output, and whether your pet can drink on its own
  • Use your phone to record video of vomiting, gait, or any abnormal behaviour for the vet's reference
  • If ingestion is suspected, contact your vet immediately or bring your pet to a clinic for assessment

03How will the vet diagnose the condition? Common tests and examinations

The vet's primary focus is assessing kidney damage, degree of dehydration, and whether hospitalisation is required — blood and urine tests are central to this.

Full physical examination to assess vital signs and degree of dehydration

Complete blood count and biochemistry panel with emphasis on kidney markers

Urinalysis (specific gravity, sediment, protein) to evaluate kidney function

Abdominal ultrasound to assess kidney structure and urinary tract changes

X-rays if needed to rule out other gastrointestinal foreign bodies or complications

Seek care at a clinic equipped to perform blood biochemistry and urinalysis

04What treatment and home care are needed after diagnosis? Medication, diet, and care guide

Poisoned pets may require hospitalisation for IV fluid therapy and ongoing monitoring; kidney function and hydration must continue to be monitored after discharge.

  • Hospitalisation for IV fluids and close vital sign monitoring may be required during the acute phase
  • Administer medications as prescribed and attend follow-up appointments to track test results
  • After discharge, continue monitoring and recording water intake, urine output, and alertness
  • Schedule regular rechecks with blood and urine tests to assess kidney recovery
  • Keep your pet away from all foods containing grapes or raisins going forward
  • If kidney function is abnormal, follow up at a clinic capable of performing nephrology tests

05What should you prepare before the vet visit? Key information to help the vet act quickly

1
Note the suspected time of ingestion, the type of food, and the estimated amount
2
Photograph or bring samples of vomit, any remaining food, or its packaging
3
Record when symptoms started, how they progressed, and your pet's current condition
4
List all current medications, supplements, and known allergies
5
Estimate and record changes in water intake and urine output for the vet's reference
6
Call ahead to a clinic equipped for emergency diagnostics or contact a pet poison control hotline

This content is for reference only and cannot replace a professional veterinary diagnosis. If your pet shows signs of illness, please seek veterinary care promptly.

Frequently Asked Questions (FAQ)