Disease Guide

Gestational Diabetes in Dogs & Cats: Symptoms, Monitoring & Treatment [2025]

Gestational diabetes is a temporary rise in blood glucose that occurs during pregnancy, driven by hormonal changes. It is most common in intact female dogs. Insulin therapy may be needed to stabilise blood sugar, and the condition typically resolves after whelping — spaying is strongly recommended.

Last updated: 2026/01/05
Pethealthmap Editorial Team
Sources: AAHA, ACVIM, National Taiwan University Veterinary Hospital

When to See a Vet

Seek Immediate Veterinary Care (Emergency)

  • Persistent inability to stand or noticeably worsening lethargy
  • Repeated vomiting or complete loss of appetite
  • Persistent excessive drinking with worsening weakness

Schedule a Veterinary Appointment Soon (Within 24-72 Hours)

  • Drinking and urination have increased significantly above normal
  • Noticeable weight loss over a short period during pregnancy
  • Reduced activity and hiding more than usual

01What symptoms should concern you?

During pregnancy, metabolic and behavioural changes — including reduced energy, altered eating habits, and shifts in drinking patterns — can be early indicators that something needs attention.

  • Lethargy and noticeably reduced activity compared to normal
  • Repeated vomiting or obvious reluctance to eat
  • Unexpected weight loss during pregnancy over a short period
  • Increased urination frequency, including waking at night to urinate
  • Significantly increased water intake (polydipsia)
  • Changes in appetite or frequent food-seeking behaviour

Seek emergency care immediately if you notice the following symptoms:

  • ⚠️ Persistent vomiting or complete refusal to eat
  • ⚠️ Rapid, noticeable weight loss accompanied by weakness
  • ⚠️ Severe lethargy or unresponsive drowsiness that does not improve

02How to monitor at home — observation tips and when to seek emergency care

Keeping a detailed home record helps your vet quickly assess your pet's condition and track how well treatment is working.

  • Record your pet's energy level and activity changes daily
  • Measure and log total daily water intake (by cup or bottle)
  • Weigh your pet at the same time each day and note the figure
  • Log vomiting episodes: time, frequency, and whether blood was present
  • Track daily urination frequency and any accidents or loss of control
  • Bring your observation log to every vet visit for the vet to review

03How will the vet make a diagnosis? Common tests and examinations

Your vet will typically start with blood glucose and urinalysis, then add imaging to assess the safety of both mother and foetuses.

Full physical examination to assess the mother's general condition and foetal wellbeing

Blood glucose measurement and complete blood count to evaluate metabolism and rule out infection

Biochemistry panel to confirm stable liver and kidney function

Urinalysis to check for glucosuria and ketonuria, indicating metabolic imbalance

Abdominal ultrasound to assess foetal count, heartbeats, and uterine condition

X-ray when necessary to evaluate foetal positioning and readiness for delivery

Referral to a specialist clinic for continuous glucose monitoring if required

04Treatment and aftercare — medications, dietary changes, and home management

Treatment focuses on stabilising blood glucose and supporting the mother and foetuses, with close monitoring of results and clinical signs to guide adjustments.

  • Insulin therapy or other medical management may be prescribed and adjusted by your vet based on response
  • A pregnancy-appropriate diet with scheduled, smaller meals to stabilise blood glucose
  • Regular follow-up visits to monitor blood glucose, biochemistry, and urinalysis
  • Ongoing home monitoring of water intake, urination, and body weight — records to share with your vet
  • Referral to a specialist hospital for further monitoring if blood glucose or clinical status fluctuates
  • Attend all scheduled check-ups and complete any required imaging or lab tests as directed

05What to prepare before the vet visit — key information to help your vet work efficiently

1
Note when symptoms first appeared and how they have progressed
2
Bring a simple daily log of water intake and urination
3
Bring a record of your pet's weight and food intake over the past two weeks
4
List all current medications and supplements your pet is taking
5
Bring any previous test results (blood work, biochemistry, or imaging) if available
6
Inform the vet of the expected due date and book a clinic that can perform blood glucose monitoring

This content is for reference only and cannot replace a professional veterinary diagnosis. If your pet shows signs of illness, please seek veterinary care promptly.

Frequently Asked Questions (FAQ)