Feline Infectious Peritonitis (FIP) in Cats: Symptoms, Diagnosis & Treatment Guide [2025]
Feline infectious peritonitis (FIP) is a life-threatening disease caused by a mutated feline coronavirus. It presents in two forms — wet (effusive) and dry (non-effusive). New antiviral therapies (GS-441524) have significantly improved remission rates.
When to See a Vet
Seek Emergency Care Immediately
- •Sudden complete weakness in the hind limbs — unable to stand or move independently
- •Persistent high fever lasting multiple days accompanied by extreme lethargy and unresponsiveness
- •Severe seizures or altered consciousness with markedly reduced response to surroundings
Schedule a Clinic Visit Soon (within 24–72 hours)
- •Noticeable weight loss over a short period with persistently reduced appetite
- •Recurrent or unstable fever that returns after subsiding
- •Changes in behavior or gait — unsteady walking or poor coordination
01What symptoms suggest something is wrong?
FIP can present in many ways and may deteriorate rapidly. Common signs include systemic illness alongside neurological or ocular abnormalities — monitor closely for sudden changes.
- Rapid and noticeable weight loss over a short period
- Recurring or persistent fever that is difficult to bring down
- Seizures, collapse, or other changes in neurological behaviour
- Unsteady gait, stumbling, or loss of coordination
- Jaundice — yellowing of the eyes, skin, or mucous membranes
Seek emergency care immediately if you notice the following symptoms:
- ⚠️ Sudden hindlimb paralysis or complete inability to move or stand
- ⚠️ High fever with severe lethargy or prolonged unresponsiveness
- ⚠️ Continuous seizures or a marked change in consciousness or responsiveness
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02How can you assess the situation at home? Key observations and when to go to emergency
Systematic home monitoring can speed up diagnosis: weigh and take temperature daily, log appetite and toileting changes, and keep photo or video records of abnormal movement or behaviour.
- Weigh your cat at a fixed time each day and track the trend
- Take your cat's temperature regularly and note the time and reading
- Record changes in appetite, food intake, and vomiting frequency
- Watch for abnormal urine or stool colour and changes in toileting habits
- Observe for any decline in alertness, activity level, or willingness to play
- Photograph or video any abnormalities and schedule a vet visit promptly
03How will the vet make a diagnosis? Common diagnostic tests
Your vet will start with a physical examination and build toward a diagnosis using blood work, imaging, and targeted tests to determine whether FIP or another condition is present.
Full physical examination, including basic neurological and ophthalmic assessment
Blood tests (complete blood count and biochemistry panel) to evaluate organ function
Specialised testing such as PCR or viral nucleic acid assays
Tissue biopsy or histopathology for definitive diagnosis when indicated
Imaging studies (ultrasound, X-ray, or advanced CT) to assess chest and abdominal changes
Consider referral to a specialist hospital capable of PCR testing and pathology
04What happens after diagnosis? Medications, dietary adjustments, and home care
FIP management follows your vet's guidance and requires close monitoring — ongoing recheck examinations are as important as the treatment itself for tracking efficacy and side effects.
- Follow the prescribed treatment plan and attend all scheduled recheck appointments
- Undergo regular blood and imaging follow-ups to monitor treatment response
- Continue tracking weight, appetite, and alertness at home between visits
- Report any suspected medication side effects to the veterinary team promptly
- Contact your vet immediately if symptoms change suddenly or worsen
05What should you prepare before the vet visit? Key information to help your vet work efficiently
This content is for reference only and cannot replace a professional veterinary diagnosis. If your pet shows signs of illness, please seek veterinary care promptly.
