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Disease Guide

Acute Kidney Injury in Dogs & Cats: Symptoms, Diagnosis & Care [2025]

Acute kidney injury is a sudden decline in kidney function that can be caused by toxins, infection, or dehydration, and requires urgent treatment to protect the kidneys.

Last updated: 2026/01/04
Pethealthmap Editorial Team
Sources: ACVIM, AVMA, National Taiwan University Veterinary Hospital

When to See a Vet

Seek emergency care immediately

  • Continuous heavy vomiting with inability to eat or drink
  • Seizures with inability to stand, or extreme lethargy
  • No urination for more than one day, or significantly reduced urine output

Schedule a clinic visit soon (within 24–72 hours)

  • Noticeably reduced appetite lasting more than 24 hours
  • Intermittent vomiting or repeated diarrhea episodes
  • Abnormally increased or decreased water intake

01What symptoms indicate something is wrong?

Acute kidney injury often presents with changes in food and water intake, along with non-specific signs such as vomiting and lethargy, requiring timely assessment of kidney function and electrolyte status.

  • Noticeably reduced appetite or complete refusal to eat, with decreased food intake
  • Frequent vomiting or ongoing diarrhea, leading to fluid and electrolyte loss
  • Significantly increased or decreased water intake, with changes in urination frequency
  • Lethargy, reduced activity, or unwillingness to play
  • Reduced urine output, changes in urine color, or abnormal urine odor
  • Atypical signs such as fever, slow heart rate, or abnormal breathing

Seek emergency care immediately if you notice the following symptoms:

  • ⚠️ If any of the above symptoms worsen rapidly, seek veterinary care immediately to prevent irreversible damage.

02How can you assess the situation at home? Key observations and when to go to the emergency clinic

Systematic home monitoring before your vet visit helps the veterinarian quickly understand the course of illness and identify possible causes.

  • Record your pet's actual daily food intake and how meal frequency changes over time
  • Note the frequency, timing, and appearance or color of any vomit
  • Monitor stool consistency, diarrhea frequency, color, and whether mucus is present
  • Measure and record body temperature (ear or rectal) if possible, and track any changes
  • Observe mental state: watch for drowsiness, weakness, or reduced activity levels
  • Track water intake and urination frequency; film urination episodes if needed

03How does the vet make a diagnosis? Common diagnostic tests

The vet combines physical examination with blood tests, urinalysis, and imaging to assess kidney function and identify possible causes.

Physical examination

assess mucous membrane color, skin turgor, and pulse quality

Blood tests

evaluate kidney markers, electrolytes, and systemic changes

Urinalysis

urine specific gravity, protein, blood, and testing for possible infection

Abdominal ultrasound

assess kidney size, structure, and urinary tract abnormalities

X-ray or CT scan if needed

evaluate organ position, urinary stones, or other structural abnormalities

Kidney biopsy may be discussed when necessary to clarify rare or unclear causes

04How is the condition treated and managed after diagnosis? Medications, dietary adjustments, and care guide

Treatment focuses on supportive care to stabilize hydration and electrolytes, with ongoing monitoring and treatment adjustments targeting the underlying cause.

  • Stabilize dehydration and electrolyte balance with supportive care such as intravenous fluids
  • Symptomatic treatments such as anti-emetics or infection control, based on veterinary judgment
  • Adjust dietary formulation based on the underlying cause and arrange short-term medication follow-up
  • Schedule regular blood and urine tests to monitor kidney function and recovery progress
  • Home care requires ongoing records of water intake, urination, and appetite changes
  • If the condition is complex or does not improve, referral to a veterinary nephrology specialist is recommended

05What should you prepare before the vet visit? Key information to help the vet identify the cause quickly

1
Note the time symptoms first appeared, the order in which they developed, and when they worsened
2
Prepare a written log of recent water intake and urination frequency
3
If possible, collect a fresh urine sample to bring to the clinic for rapid testing
4
Film any vomiting, abnormal urination, or reduced activity episodes for the vet to review
5
List all current medications, supplements, and a detailed feeding history
6
Bring past blood test, urine test, or imaging reports if available

This content is for reference only and cannot replace a professional veterinary diagnosis. If your pet shows signs of illness, please seek veterinary care promptly.

Frequently Asked Questions (FAQ)