Disease Guide

Blastomycosis in Dogs & Cats: Weight Loss, Respiratory Symptoms, Diagnosis & Treatment [2025]

Blastomycosis is a serious fungal infection common in moist environments that requires long-term antifungal treatment

Last updated: 2026/01/05
Pethealthmap Editorial Team
Sources: ACVIM, WSAVA, National Taiwan University Veterinary Hospital

When to See a Vet

Seek immediate emergency care

  • Persistent rapid breathing with visible signs of respiratory distress
  • Repeated seizures or sudden collapse and loss of responsiveness
  • Gums or lips turning purple or white with abnormal coloration

Schedule a clinic visit soon (within 24–72 hours)

  • Persistent weight loss without an obvious cause
  • Persistent fever or abnormal body temperature with otherwise stable behavior
  • Recurrent coughing or a noticeable increase in coughing frequency

01What symptoms signal a problem?

Blastomycosis can affect the respiratory, systemic, and nervous systems; common signs include weight loss, fever, and respiratory symptoms.

  • Persistent, unexplained weight loss
  • Recurrent or persistent fever — record temperature changes
  • Recurrent or worsening cough, or dry hacking cough
  • Increased breathing rate, laboured breathing, or respiratory distress
  • Seizures, abnormal gait, or other neurological signs
  • Localised or generalised swelling, or palpable lumps
  • If any of the above occur, arrange a clinic assessment as soon as possible

Seek emergency care immediately if you notice the following symptoms:

  • ⚠️ Difficulty breathing or severe respiratory distress requires immediate veterinary care
  • ⚠️ Repeated seizures, collapse, or loss of consciousness — go to an emergency clinic immediately
  • ⚠️ Purple or white gums indicate an emergency — seek urgent care

02How can you monitor at home? Key observations and when to go to emergency

Recording observations at home helps your vet quickly understand the disease progression and plan diagnostic steps.

  • Weigh your pet at the same time each day and record the result
  • Take temperature at regular intervals and note the time and reading
  • Log cough frequency, duration, and any triggers
  • Monitor breathing rate and note any effort or pausing
  • Assess changes in alertness, energy level, and responsiveness
  • Track appetite and water intake changes and bring the notes to your appointment
  • Share your notes or video clips with the vet as a clinical reference

03How will the vet diagnose this? Common diagnostic tests

After a physical examination, the vet will combine blood work, imaging, and cytology to identify the source of infection and affected organs.

Full physical examination

assessment of respiratory, cardiac, and systemic status

Complete blood count (CBC)

checking for infection or inflammatory response

Biochemistry panel

evaluation of liver, kidney, and other organ function

Cytology or histopathology

sampling to characterise the lesion

Chest X-ray or CT scan

assessment of pulmonary or thoracic lesions

Fungal culture or special staining when needed to confirm the pathogen

Referral to a clinic with infectious disease or internal medicine expertise is recommended

04What treatment and care are needed after diagnosis? Medication, diet, and home care guide

Treatment focuses on controlling the infection and supporting respiratory function and nutrition, with regular follow-up to assess response and side effects.

  • Your vet will prescribe appropriate antifungal or supportive treatment based on assessment
  • Oxygen supplementation may be provided if needed to support breathing
  • Dietary adjustment and nutritional support to assist weight recovery
  • Schedule regular recheck appointments with repeat imaging or bloodwork to monitor progress
  • Home care focuses on rest, a calm environment, and minimising additional stress
  • Return to the clinic or seek referral promptly if the condition worsens or new symptoms appear

05What should you prepare before your vet visit? Key information to help the vet identify the cause quickly

1
Note when symptoms started and how they have changed day by day
2
Bring weight and appetite records from the past few days
3
Take photos of any stool, urine, or skin lesion changes for reference
4
List all current and recent medications and supplements
5
Bring any previous test reports or imaging if available
6
Record a video or audio clip if your pet is coughing or breathing abnormally
7
Call ahead to book an appointment or arrange a specialist consultation slot

This content is for reference only and cannot replace a professional veterinary diagnosis. If your pet shows signs of illness, please seek veterinary care promptly.

Frequently Asked Questions (FAQ)